Arsenal has been dealt another major injury setback which has left Mikel Arteta with a "big worry" as his side looks to chase down Liverpool in the Premier League.

Mikel Arteta has been told he must replace Gunners striker Kai Havertz after Arsenal were knocked out of the FA Cup by Manchester United. Arsenal are the most successful team in FA Cup history but will not be adding to their 14 trophies after losing on penalties to United at the Emirates Stadium.

Mikel Arteta described Arsenal's FA Cup third-round defeat to Manchester United on Sunday as a one-in-a-thousand occurrence after losing in a dramatic penalty shootout at Emirates Stadium. Bruno Fernandes put the visitors in front on 52 minutes before Diogo Dalot was sent off nine minutes later for a late tackle on Mikel Merino.